Comments:

Cochrane Database Syst Rev. 2008;(4):CD000487.

Abstract:

A quote of results from the group's conclusions: " Some months of adjuvant polychemotherapy (eg, with CMF or an anthracycline-containing regimen) typically produces an absolute improvement of about 7-11% in 10-year survival for women aged under 50 at presentation with early breast cancer, and of about 2-3% for those aged 50-69 (unless their prognosis is likely to be extremely good even without such treatment). Treatment decisions involve consideration not only of improvements in cancer recurrence and survival but also of adverse side-effects of treatment, and this report makes no recommendations as to who should or should not be treated.

Rights:

http://www.ncbi.nlm.nih.gov/pubmed/11869577

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11869577
EarlyBreastCancer_multichemotherapy.pdf

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